Hide all drives from My Computer

Step 1. Go to Start -> Run. 

Step 2. Type regedit

Step 3. Now go to:
            HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Policies\Explorer

Step  4. Now in the right pane, create a new DWORD item and name it NoDrives (it is case sensitive).

Step  5. Now modify it's value and set it to 3FFFFFF (Hexadecimal) .

Step  6. Now restart your computer. 

Step  7. So, now when you click on My Computer, no drives will be shown(all gone...).

To enable display of drives,simply delete this DWORD item that you created. Again restart your computer. You can now see all the drives again